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In the treated group PGI increased remarkably, synthesis of TXA was inhibited, cAMP in platelets was elevated, CK MB peak was lowered and appeared earlier, ELT was shortened, release of platelet beta GT was decreased, platelet maximum Elecom rate was inhibited, the size of ischemic area recorded by epicardial ECG was reduced, the amplitude of ST segment elevation was lower than that in the control group, Q wave appeared in only one dog. Ml per kg body weight reduced the number of microfilariae in blood by more than.

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